Electroproduction of the d* dibaryon

The unpolarized cross section for the electroproduction of the isoscalar $J^\pi = 3^+$ di-delta dibaryon $d^*$ is calculated for deuteron target using a simple picture of elastic electron-baryon scattering from the $\Delta \Delta (^7D_1)$ and the $NN (^3S_1)$ components of the deuteron. The calculated differential cross section at the electron lab energy of 1 GeV has the value of about 0.24 (0.05) nb/sr at the lab angle of 10$^\circ$ (30$^\circ$) for the Bonn B potential when the dibaryon mass is taken to be 2.1 GeV. The cross section decreases rapidly with increasing dibaryon mass. A large calculated width of 40 MeV for $d^*(\Delta\Delta ^7S_3)$ combined with a small experimental upper bound of 0.08 MeV for the $d^*$ decay width appears to have excluded any low-mass $d^*$ model containing a significant admixture of the $\Delta\Delta (^7S_3)$ configuration.Comment: 11 journal-style pages, 8 figure

Polarimetric Observations of 15 AGNs at High Frequencies

Original paper can be found at: http://www.astrosociety.org/pubs/cs/328.html--Copyright Astronomical Society of the PacificWe have obtained total and polarized intensity images of 15 AGNs with the VLBA at 7 mm at 17 epochs from 25/26 March 1998 to 14 April 2001. The VLBA observations are accompanied at many epochs by simultaneous mea- surements of polarization at 1.35/0.85 mm as well as less frequent simultaneous optical polarization measurements. We discuss the similarities and complexities of polarization behavior at different frequencies along with the VLBI properties

Direct Speech Reconstruction From Articulatory Sensor Data by Machine Learning

This paper describes a technique that generates speech acoustics from articulator movements. Our motivation is to help people who can no longer speak following laryngectomy, a procedure that is carried out tens of thousands of times per year in the Western world. Our method for sensing articulator movement, permanent magnetic articulography, relies on small, unobtrusive magnets attached to the lips and tongue. Changes in magnetic field caused by magnet movements are sensed and form the input to a process that is trained to estimate speech acoustics. In the experiments reported here this “Direct Synthesis” technique is developed for normal speakers, with glued-on magnets, allowing us to train with parallel sensor and acoustic data. We describe three machine learning techniques for this task, based on Gaussian mixture models, deep neural networks, and recurrent neural networks (RNNs). We evaluate our techniques with objective acoustic distortion measures and subjective listening tests over spoken sentences read from novels (the CMU Arctic corpus). Our results show that the best performing technique is a bidirectional RNN (BiRNN), which employs both past and future contexts to predict the acoustics from the sensor data. BiRNNs are not suitable for synthesis in real time but fixed-lag RNNs give similar results and, because they only look a little way into the future, overcome this problem. Listening tests show that the speech produced by this method has a natural quality that preserves the identity of the speaker. Furthermore, we obtain up to 92% intelligibility on the challenging CMU Arctic material. To our knowledge, these are the best results obtained for a silent-speech system without a restricted vocabulary and with an unobtrusive device that delivers audio in close to real time. This work promises to lead to a technology that truly will give people whose larynx has been removed their voices back

Use of sieving as a valuable technology to produce enriched buckwheat flours: A preliminary study

Fractionation processes based on physical separation are a good strategy to produce enriched cereal flours. Therefore, the aim of this work is to evaluate the suitability of sieving of buckwheat flours to produce protein and phenolic (especially rutin) enriched fractions. Because of that, dehulled whole buckwheat flour (GSTQ) was sieved obtaining fractions with a particle size of 215 \uf06dm, 160 \uf06dm, 85 \uf06dm, and 45 \uf06dm (GS215, GS160, GS85, and GS45). For that purpose, the determination of protein, ash, and total starch content and free and bound phenolic compounds was carried out. The highest content of total phenolic compounds was obtained in GS215 (3118.84 mg kg-1 d.w.), followed by GS160 (2499.11 mg kg-1 d.w.), GS85 (989.46 mg kg-1 d.w.), GSTQ (983.15 mg kg-1 d.w.), and GS45 (481.31 mg kg-1 d.w.). Therefore, the phenolic content decreased with the particle size decrease from 215 \uf06dm to 45 \uf06dm. Besides, there were no significant differences between the total phenolic content in GS85 and GSTQ. The fraction with 215 \uf06dm reported the highest protein and mineral salt content and presented rutin amounts four times higher than GSTQ

Tratamiento de aguas residuales procedentes de la industria farmacéutica mediante nano-fotocatálisis con TiO2

Durante la fabricación de fármacos, se generan aguas residuales que pueden contener restos de materias primas, productos intermedios o productos finales, contaminantes emergentes de efectos ambientales todavía desconocidos que deben de ser eliminados previamente a su vertido final. Actualmente se estudia el tratamiento de aguas con contaminantes orgánicos oxidables mediante procesos de oxidación avanzada, entre los que destaca la fotocatálisis heterogénea. El dióxido de titanio es el semiconductor más indicado para usar en el tratamiento fotocatalítico del agua debido a su baja toxicidad, resistencia a la fotocorrosión, disponibilidad, efectividad y relativo bajo cost

17. EL APRENDIZAJE INTEGRAL A TRAVÉS DE LA STEM, REFLEXIONES SOBRE SU APLICACIÓN EN LA EDUCACIÓN EN LAS INSTITUCIONES EDUCATIVAS EN MEDELLÍN

Medellín reconocida como la ciudad innovadora del mundo y epicentro de la cuarta revo­lución industrial, tiene un reto y un compromiso con estos dos momentos, modernizar la educación apor­tando al desarrollo de habilidades de pensamiento enfocados a la ciencia y la tecnología, y promover en todos los entornos habilidades para la vida. Uno de los desafíos más importantes en la educación es el desarrollo de una formación integral, lograr que los estudiantes y maestros, apropien disciplinas que necesitan para un desarrollo más sistémico en lo profesional. STEM por sus siglas en ingles Science, Technology, Engineering and Mathematics, es una metodología que posiblemente se ha aplicado en el entorno local, sin darle la connotación que tiene, considerada necesaria para el eficiente desarrollo de los profesionales del futuro. Las disciplinas que se agrupan en esta metodología permiten integrar habilidades duras y blandas en un solo ejercicio, buscando desarrollar competencias necesarias para responder a las actuales necesidades del mercado. El objetivo de esta propuesta de reflexión es realizar una revisión sobre la aplicación de la metodología STEM en la educación en Medellín, aplicando la metodología sistemática para hacer el rastreo y la revisión bibliográfica

Dietary supplementation with methyl donors reduces fatty liver and modifies the fatty acid synthase DNA methylation profile in rats fed an obesogenic diet

Non-alcoholic fatty liver disease (NAFLD) is one of the first hepatic manifestations of metabolic syndrome, whose progression can lead to cirrhosis and hepatic carcinoma. Interestingly, methyl donor supplementation could improve obesogenic diet-induced hepatic triglyceride accumulation. The aim of this research is to describe methyl donor effects on a high-fat-sucrose (HFS) diet in both sexes and epigenetic changes induced on fatty acid synthase (FASN) promoter methylation pattern as well as gene expression of NAFLD key metabolic genes. Twenty-four male and 28 female Wistar rats were assigned to three dietary groups: control, HFS, and HFS supplemented with methyl donors (choline, betaine, vitamin B12, and folic acid). After 8 weeks of treatment, somatic, biochemical, mRNA, and epigenetic measurements were performed. Rats fed the HFS diet presented an overweight phenotype and alterations in plasma biochemical measurements. Methyl donor supplementation reverted the HFS-diet-induced hepatic triglyceride accumulation. Analysis of FASN promoter cytosine methylation showed changes in both sexes due to the obesogenic diet at -1,096, -780, -778, and -774 CpG sites with respect to the transcriptional start site. Methyl donor supplementation modified DNA methylation at -852, -833, -829, -743, and -733 CpGs depending on the sex. RT-PCR analysis confirmed that FASN expression tended to be altered in males. Our findings reinforce the hypothesis that methyl donor supplementation can prevent hepatic triglyceride accumulation induced by obesogenic diets in both sexes. Changes in liver gene expression profile and epigenetic-mediated mechanisms related to FASN DNA hypermethylation could be involved in methyl donor-induced NAFLD improvement

Higher Dimensional Recombination of Intersecting D-branes

We study recombinations of D-brane systems intersecting at more than one angle using super Yang-Mills theory. We find the condensation of an off-diagonal tachyon mode relates to the recombination, as was clarified for branes at one angle in hep-th/0303204. For branes at two angles, after the tachyon mode between two D2-branes condensed, D2-brane charge is distributed in the bulk near the intersection point. We also find that, when two intersection angles are equal, the off-diagonal lowest mode is massless, and a new stable non-abelian configuration, which is supersymmetric up to a quadratic order in the fluctuations, is obtained by the deformation by this mode.Comment: 18 pages, 2 figures, JHEP style. v3:references added, minor corrections, English improve

Effects of peroxisome proliferator-activated receptor- activation in endothelin-dependent hypertension

Aims We analysed the chronic effects of the peroxisome proliferator-activated receptor β/δ (PPAR-β) agonist GW0742 on the renin-independent hypertension induced by deoxycorticosterone acetate (DOCA)-salt. Methods and results Rats were treated for 5 weeks with: control-vehicle, control-GW0742 (5 or 20 mg kg−1 day−1), DOCA-vehicle, DOCA-GW0742 (5 or 20 mg kg−1 day−1), DOCA-GSK0660 (1 mg kg−1 day−1), and DOCA-GSK0660-GW0742. Rats receiving DOCA-vehicle showed increased systolic blood pressure, left ventricular and kidney weight indices, endothelin-1 (ET-1), and malondialdehyde plasma levels, urinary iso-PGF2α excretion, impaired endothelium-dependent relaxation to acetylcholine, and contraction to ET-1 when compared with controls. Aortic reactive oxygen species content, NADPH oxidase activity, and p47phox, p22phox, NOX-4, glutathione peroxidase 1, hemeoxygenase-1, and preproET-1 expression were increased, whereas catalase and regulators of G protein-coupled signalling proteins (RGS)5 expression were decreased in the DOCA-vehicle group. GW0742 prevented the development of hypertension in a dose-dependent manner but the reduction of renal and cardiac hypertrophy, systemic and vascular oxidative stress markers, and improvement of endothelial dysfunction were only observed after the higher dose. GW0742, at 20 mg kg−1 day−1, attenuated ET-1 contraction by increasing RGS5 expression and restored the intracellular redox balance by reducing NADPH-oxidase activity, and by increasing the antioxidant genes expression. The PPAR-β antagonist GSK0660 prevented all vascular changes induced by GW0742 but not its antihypertensive effects. Conclusion Vascular protective effects of GW0742 operate via PPAR-β by interference with the ET-1 signalling as a result of increased expression of RGS5 and up-regulation of antioxidant genes and via PPAR-β-independent mechanisms to decrease blood pressure